It's possible that maybe Nick was talking about romances between CSIs, not necessarily the lab in general.
But I do think they would be great together - I can see them being good for one another.
I think that would actually add a interesting spin on it. Nicks so against dating someone he works with, so what would be a interesting situation to put him in? Yup, and Mandy's the perfect one.
I like how pally they are and seriously anyone else would either seriously creep me out (catherine - thats like his mom
, riley - way too young and they don't click and theres no flowy banter like mandy and nick, or wendy - that would just be mean on hodges and she's too different).
Mandy's down to earth and the only female labrat I can imagine him hanging out with or yelling at a football game together with a couple of beers. Some of the scenes they have together they just seem completly in tune, like if they suddenly started finishing each others sentences I likely wouldn't notice until much later as some of the time it sounds like that already.
I don't think they realise what they have with mandy. Shes like the ultimate flagship for a slightly different picture of beauty. She's still beautiful but in a less anorexic looking, blonde, cheek bones you could poke your eyes out with bimbo looking way. I think her slightly different body shape and huge personality would really get the admiration of so many females that don't fit the culteral model looks (which is most).
I'm not saying, good lord get them together now (that always ends in a angst hate filled break up). It would be nice if they set some foundations of at least some hints they socialise outside of work, like the time the csi team went go-carting with the cornener.