Supernatural
Dean: I barely have any skin left on my palm.
Sam: I'm not touching that line with a ten foot pole.
Sam: Dean, there's ten times as much lore about angels as there is about anything else we've ever hunted.
Dean: You know what, there's a ton of lore on unicorns too. In fact, I hear that they ride on silver moonbeams, and that they shoot rainbows out of their ass!
Sam: Wait, there's no such thing as unicorns?
Dean
Looking at a haunted hotel) We might even run into Fred and Daphne inside. Mmmm... Daphne. Love her.
Dean: Ya' know she could be faking.
Sam: Yeah, what do you wanna do, poke her with a stick? Dude, you're not gonna poke her with a stick!
Dean
after security guard says okie dokie) I like him, he says okie dokie.
Sam: Dude, I'm not enabling your sick habit. You're like one of those lab rats that pushes the pleasure button instead of the food button until it dies.
Dean: What are you talking about, I eat.
Sam: Why'd you let me fall asleep?
Dean: Because I am an awesome brother. What did you dream about?
Sam: Lollipops and candycanes.
Dean: I thought the legend said that Morteki only goes after chicks.
Sam: He does.
Dean: Right well that explains we he went after you but why me?
Dean: People believe in Santa Claus... why aren't I getting hooked up every Christmas?
Sam: 'Cause you're a bad person.
Ed: This stuff right here, this, is our ticket to the big time. Fame, money, sex. With girls! OK, be brave, OK. W.W.B.D. What would Buffy do?
Harry: What would Buffy do. I know, but Ed, she's stronger that me.
Ed: It's OK.
Psych
Shawn: Collecting money for the Policeman's ball?
Lassiter: We don't have balls.
Henry: What about your license?
Shawn: My pilot's license? Out back in my Cessna. Or perhaps you're referring to my license to kill. Revoked. Problems at the Kazakhstan border. I could give you details, but then I would have to kill you which I can't do because my licence to kill was revoked
Carlton Lassiter: We found prints.
Shawn: Was he in a little red corvette?
Gus: Under the cherry moon?
Lassiter: Finger prints
Shawn: Gus, she found another doctor. She's seeing him today!
Gus: When?
Shawn: Right now!
Gus: Right now, Shawn?
Shawn: Like in ten minutes.
Shawn: Oh, yes. Yes, I'm definitely feeling something here. Oh, it's good. It's nice!
Leslie: What? What is it?
Shawn: This mattress. It feels like one of those mattresses where you can bounce a bowling ball but the glass of wine doesn't spill. Gus, go find a glass of wine and a bowling ball.
Gus: So... The prophecy has been fulfilled.
Shawn: Hmm. What? What are you talking about? What prophecy?
Gus: Nothing. I just figured it was finally my chance to say something dramatic