This is from Vegaslights posted in the spoiler thread about the episode.
~ The episode starts off with Horatio and Tripp on an airplane. Jack McNeil, a fugitive, is in their custody and they're in the process of escorting him from the Bahamas to Miami International. Horatio notices something not quite right with the flight pattern, so he talks to the captain who assures him that everything is according to plan. As Horatio makes his way back to his seat, Tripp notices a gun. The flight crew start firing bullets at Horatio and Tripp (including the plane's captain).
~ The plane crashes. Horatio rushes over to Tripp, who is bleeding badly. McNeil somehow escapes.
~ Patrick Clarkson from 9.18 emerges as a connection to the case. Jack somehow helped Patrick escape from prison, and while Patrick is grateful for all of Jack's help, he isn't willing to return the favor.
~ There's a counterfeiting ring in connection to Jack. Agent Lockhart assists the team in capturing Jack.
In bold - That's what's making me think something could go down in the courtroom at the end of the episode, & Natalia could get caught up in it.
Overall, I think it could be any of these 4 listed:
Horatio
Natalia
Ryan (for some reason I can't see it being his time to be hospitalized though)
Renee
I'm not going to include Frank because even if he is shot during the plane crash, that happens in the beginning of the episode & I highly doubt he'll be shot twice in the same episode....plus, I believe spoilers said that Frank pulls out from the team just when Horatio needs him the most.
As for the others --
Walter - no, not enough going on with him.
Eric - only if he just so happens to be there & is hit in the arm or something. I don't see him in peril again -- appear to be 'down'? Maybe. But not actually injured.
Calleigh - only if changes in casting is coming, otherwise it's doubtful she'd be shot.