I've been reading for the past year or so that Laurie was ready to call it quits, so I wasn't too surprised by this. I was more worried that FOX wouldn't let it go. With the rollercoaster this show has been though, I can't even imagine how it will conclude. I think it would be fitting for House to die; I just don't see a happy ending for him, or any of David Shore's characters, honestly. I would love to see Cuddy and Cameron and Thirteen return, even if briefly. All three of these women had an interesting relationship with House. I'll miss the show, but I think it's time. However House goes out, I'm sure it will be memorable.